Prognostic Value of Histology and Lymph Node Status in Bilharziasis-bladder Cancer: Outcome Prediction Using Neural Networks
نویسندگان
چکیده
In this paper, the evaluation of two features in predicting the outcomes of patients with bilharziasis bladder cancer has been investigated using an RBF neural network. Prior to prediction, the feature subsets were extracted from the whole set of features for the purpose of providing a high performance of the network. Throughout the analysis of the prognostic feature combinations, two features, histological type and lymph node status, have been identified as the important indicators for outcome prediction of this type of cancer. The highest predictive accuracy reached 85.0% in this study.
منابع مشابه
بررسی رابطه بین شاخص توموری 2-Her و قدرت تهاجمی سرطان پستان(متاستاز به غدد لنفاوی زیر بغل) در بیماران ماستکتومی شده در انستیتو کانسر طی سالهای 82-1380
Breast cancer is the most common site-specific cancer and is the second cause of mortality due to cancer in women. There are different prognostic factors including: axillary nodal status and tumor size(the most important factor), ER activity, PR, tumor grade and the type of histology. Other incompletely defined risk factors are: protease, catepstin, Her-2, etc. Her-2 is subtype 2 of E...
متن کاملPrognostic Value of Lymph Node Ratio in comparison to Lymph Node Metastases in Stage III Colon Cancer
Background & Objectives: Colon cancer is currently of high incidence and mortality rate. Identifying the factors influencing its prognosis can be very beneficial to its clinical treatment. Recent studies have shown that lymph nodes ratio can be considered as an important prognostic factor. The aim of the present study is to investigate the effect of this factor on the prognosis of the ...
متن کاملCD8+ T Lymphocyte Subsets in Bladder Tumor Draining Lymph Nodes
Background: Cytotoxic CD8+ T cells, as essential parts of the adaptive immune system, play pivotal roles in anti-tumor immune responses. It is well documented that cytokine expression profiles and activation status of these cells during anti-tumor immune responses affect the outcome of host-tumor interaction. Objective: To investigate the percentages of CD8+ lymphocytes and their subsets in...
متن کاملPrediction of nodal metastasis and prognosis of breast cancer by ANN-based assessment of tumour size and p53, Ki-67 and steroid receptor expression.
BACKGROUND Tumour stage and the appropriate course of treatment in patients with breast cancer are primarily characterized by the state of metastasis in the axillary lymph nodes. In recent years, substantial research has focused on the prediction of lymph node status based on various pathological and molecular markers in order to obviate the necessity to carry out axillary dissection. In the pr...
متن کاملعوامل مؤثر بر بقاء بیماران مبتلا به سرطان کولورکتال با استفاده از توابع مفصل
Background & objectives: Competing risk data is one of the multivarite survival data. Competing risk data can be modelled using copula function. In this study we propose a bayesian modelling approach of competing risk data using the copula function.Methods: We used the data from colorectal cancer registyrarty in Tehran. After constructing likelihood function using Clayton copula by choosing app...
متن کامل